Identification of tp53 mutations in circulating tumour dna in high grade serous ovarian carcinoma using next generation sequencing technologies

HIGHLIGHTS

• who: Leslie Calapre from the SchoolCowan University, Joondalup, WA, Australia have published the article: Identification of TP53 mutations in circulating tumour DNA in high grade serous ovarian carcinoma using next generation sequencing technologies, in the Journal: Scientific Reports Scientific Reports
• what: The study demonstrates the utility of a UMI-tagged NGS panel for plasma TP53 mutation screening in HGSOC patients.
• how: The authors collected blood samples from 10 stage III and IV HGSOC patients with active disease enrolled for study in 2018 at Western Oncology Clinic and Sir Charles Gairdner Hospital (SCGH) in . . .
  

   

  

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