The role of macrophages-mediated communications among cell compositions of tumor microenvironment in cancer progression

HIGHLIGHTS

  • who: Mengyuan Li et al. from the Emory University, United States have published the Article: The role of macrophages-mediated communications among cell compositions of tumor microenvironment in cancer progression, in the Journal: (JOURNAL)
  • future: The exact mechanism of CAFs and TAMs interaction remains undefined further investigation is required for therapeutic exploitation.

SUMMARY

    TME is a complex environment that is mainly composed of tumor cells and various immune cells, such as T_cells, tumor-associated macrophages (TAMs), natural killer (NK) cells, neutrophils, dendritic cells (DCs), B lymphocytes and cancer-associated fibroblasts (CAFs . . .

     

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