Mendelian randomization reveals no associations of genetically-predicted obstructive sleep apnea with the risk of type 2 diabetes, nonalcoholic fatty liver disease, and coronary heart disease

HIGHLIGHTS

  • who: Xiaoxu Ding from the University, China have published the research work: Mendelian randomization reveals no associations of genetically-predicted obstructive sleep apnea with the risk of type 2 diabetes, nonalcoholic fatty liver disease, and coronary heart disease, in the Journal: (JOURNAL)
  • what: We have to clarify several limitations for future investigations: (1) Horizontal pleiotropy is the main issue in MR analysis and our study is no exception.
  • how: Besides the MR results indicated that genetically-predicted OSA could not be directly associated with the risk of NAFLD IVW p=0.501] . The . . .

     

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