Drug-loaded microbubble delivery system to enhance pd-l1 blockade immunotherapy with remodeling immune microenvironment

HIGHLIGHTS

  • who: Jun Zheng from the State Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, Peopleu2019s Republic of China have published the research: Drug-loaded microbubble delivery system to enhance PD-L1 blockade immunotherapy with remodeling immune microenvironment, in the Journal: (JOURNAL)
  • what: Docetaxel R837 DTX/R837 coloaded microbubbles u03b1PD-L1 Anti-Programmed Cell Death-Ligand 1 antibody ICB Immune checkpoint blockade UTMD Ultrasound-targeted microbubble destruction TAMs Tumor-associated macrophages Treg Regulatory T_cells MDSCs Myeloid-derived suppressor cells TAAs Tumor-associated antigens APC Antigen-presenting cell TME Tumor microenvironment ICD Immunogenic . . .

     

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