Chrna5 and lynx prototoxins identify acetylcholine super-responder subplate neurons

HIGHLIGHTS

  • who: Sridevi Venkatesan from the of Physiology, Temerty Faculty of Medicine, University of Toronto, King`s College Circle, Toronto, ON, Canada have published the article: Chrna5 and lynx prototoxins identify acetylcholine super-responder subplate neurons, in the Journal: (JOURNAL) of February/17,/2023
  • what: The authors demonstrate a large fraction of Chrna5+ neurons have distinctive high-affinity cholinergic responses. The authors focused on the Chrna5+, Syt6+, and Chrna5+Syt6+ groups to examine their transcriptomic differences. The work examines the effects of GPI-anchored lynx prototoxins on native nicotinic receptor-mediated optogenetic responses, advancing from work . . .

     

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