Recent developments in nsg and nrg humanized mouse models for their use in viral and immune research

HIGHLIGHTS

• who: Maksym Kitsera et al. from the Bernhard-Nocht Institute for Tropical Medicine, Hamburg, Germany have published the research: Recent Developments in NSG and NRG Humanized Mouse Models for Their Use in Viral and Immune Research, in the Journal: Viruses 2023, 478 of /2023/
• what: Due to the spontaneous generation of mouse T-, B-, and NK cells during aging, this model had a limited capacity to efficiently and long-term engraft human cells . The main feature of this model is that the generated humanized mouse retains the immune memory of the donor cells. The authors . . .
  

   

  

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