Mirna-induced downregulation of ipmk in macrophages mediates lipopolysaccharide-triggered tlr4 signaling

HIGHLIGHTS

  • who: Haein Lee et al. from the Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea have published the article: miRNA-Induced Downregulation of IPMK in Macrophages Mediates Lipopolysaccharide-Triggered TLR4 Signaling, in the Journal: Biomolecules 2023, 13, 332. of /2023/
  • what: This study provides evidence supporting that IPMK expression in macrophages is transcriptionally suppressed under LPS stimulation.
  • how: Similar results were obtained using mouse bone-marrow-derived macrophages (BMDMs) .

SUMMARY

    Inositol polyphosphate multikinase (IPMK) is a versatile signaling factor showing pleiotropic . . .

     

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