Importin-mediated pathological tau nuclear translocation causes disruption of the nuclear lamina, tdp-43 mislocalization and cell death

HIGHLIGHTS

• who: Alejandra D. Alonso from the Department of Biology, Center for Developmental Neuroscience, College of Staten Island, The City University of New York, United States, Department of Biological Sciences, Wagner College, Staten Island, NY, United States have published the paper: Importin-Mediated Pathological Tau Nuclear Translocation Causes Disruption of the Nuclear Lamina, TDP-43 Mislocalization and Cell Death, in the Journal: (JOURNAL)
• what: The authors report that PH-tau localizes strongly to the nucleus . The authors report a significant decrease in the mean fluorescence intensity of lamin only in PH-tau-positive cells, suggesting a . . .
  

   

  

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