Preferred β-lactone synthesis can explain high rate of false-negative results in the detection of oxa-48-like carbapenemases

HIGHLIGHTS

  • who: Vendula Studentova from the Charles University have published the research work: Preferred u03b2-lactone synthesis can explain high rate of false-negative results in the detection of OXA-48-like carbapenemases, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    Bacterial isolates, susceptibility testing. Previously well characterized 74 isolates of carbapenem Carbapenemase detection by MALDI‑TOF MS analysis, Carba NP test, and modified carbapenem inactivation method (CIM). Carbapenemase activity was detected by the MALDI-TOF MS mero- penem hydrolysis assay, Carba NP test, and modified Carbapenem Inactivation Method (mCIM) as previously ­described26-28 . . .

     

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