A highly sensitive nanoluc-based protease biosensor for detecting apoptosis and sars-cov-2 infection

HIGHLIGHTS

• who: Masashi Arakawa from the DepartmentHirosaki University have published the paper: A highly sensitive NanoLuc-based protease biosensor for detecting apoptosis and SARS-CoV-2 infection, in the Journal: Scientific Reports Scientific Reports
• what: The authors successfully established a novel protease reporter system based on highly sensitive NanoLuc luciferase.
• how: In this study HiBiT was used instead of nLuc (u03b210). These results indicated that u03b29-E5- u03b210 and u03b21-8 were assembled in a TEV cleavage-dependent manner as expected. The authors evaluated the FlipNanoLuc protease biosensor as an indicator of caspase activity . . .
  

   

  

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