HIGHLIGHTS
- who: Samir Sarikouch from the University of Padua, Italy have published the research: Serial assessment of early antibody binding to decellularized valved allografts, in the Journal: (JOURNAL)
SUMMARY
Despite almost complete decellularization, documented by standard microscopy and very low residual DNA content, DHV seem to elicit an immune_response that appears to be stronger in younger recipients, indicated by progressing valve dysfunction. Classic T-cellmediated immune_response, considered to be the leading mechanism for the usually relatively slow mode of degeneration in cryopreserved heart valves, may not be the key mechanism in DHV degeneration. A . . .
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