Thioredoxin-interacting protein in diabetic retinal neurodegeneration: a novel potential therapeutic target for diabetic retinopathy

HIGHLIGHTS

  • who: Zhengshuai Lv and Li Kong and Xiang Ren from the University of Bern, Switzerland have published the paper: Thioredoxin-interacting protein in diabetic retinal neurodegeneration: A novel potential therapeutic target for diabetic retinopathy, in the Journal: (JOURNAL)

SUMMARY

    An increasing number of studies have shown that DRN plays a pivotal role in the pathogenesis of DR and occurs earlier and more insidiously than microvascular lesions (Jonsson et_al, 2016; Kadłubowska et_al, 2016). The signal is transmitted to the nucleus, binding to ChoRE to activate the TXNIP promoter and promoting TXNIP gene transcription . . .

     

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