Structural modi cations of berberine and their binding effects towards polymorphic deoxyribonucleic acid structures: a review

HIGHLIGHTS

  • who: . and collaborators from the University of Tehran, Iran have published the paper: Structural modi cations of berberine and their binding effects towards polymorphic deoxyribonucleic acid structures: A review, in the Journal: (JOURNAL)
  • how: The results indicated that 3 possessed quite high DNA-binding affinities attributed to the multivalent interactions between the polyamino groups and DNA. The results showed that all the compounds including BBR induced cooperatively self-structure formation in poly(A). The results showed that the binding affinity of 21 for G4 DNA is modest.

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