Eef2k inhibitor design: the progression of exemplary structure-based drug design

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  • who: Kody A. Klupt and Zongchao Jia from the Department of Biomedical and Molecular Sciences, Queen`s University, Kingston, ON K L, Canada have published the research work: eEF2K Inhibitor Design: The Progression of Exemplary Structure-Based Drug Design, in the Journal: Molecules 2023, 1095 of /2023/
  • what: Using available crystal structures of related u03b1-kinases particularly the authors report how homology modeling has been used to improve inhibitor design and efficacy. This review presents an overview of eEF2K related drug discovery efforts predating from the 1990`s to more recent in vivo studies in . . .

     

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