HIGHLIGHTS
SUMMARY
Univariate cox analysis was used for the 50 hypoxic genes, and genes with P and amp;lt; 0.05 were secondarily screened out for later research. Immune cells in patients at high-hypoxia-risk are suppressed, such as T_cells CD4 memory activated and T_cells follicular helper (Fig 4B, J). The results of ssGSEA analysis further suggested that the infiltration levels of B cells, macrophages, neutrophils, T helper cells, NK cells and regulatory T_cells (Tregs) were significantly increased in the high-hypoxia-risk group (Fig 4M). The six hypoxic genes were positively correlated to CD4 . . .
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