Sptbn1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a gpt2-dependent manner

HIGHLIGHTS

  • who: Jiajin Wu from the Department of Urology, The First Affiliated Hospital of Nanjing Medical Province Hospital, No, Guangzhou Road, Nanjing, China have published the research: SPTBN1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a GPT2-dependent manner, in the Journal: (JOURNAL)
  • what: The research demonstrated that SPTBN1 is significantly down-regulated in ccRCC. The authors aimed to investigate the aberrant expression pattern of SPTBN1 in ccRCC and its tumor-suppressive role, as well as its interaction with downstream GPT2 to suppress tumor-required glycolysis.
  • how: The results showed that . . .

     

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