Ferroptosis—a novel mechanism with multifaceted actions on stroke

HIGHLIGHTS

  • who: Xiao-Zheng Du and Jin-Hai Wang from the College of Acupuncture and Massage, Gansu University of Traditional Chinese Medicine, Lanzhou, China, Department of have published the Article: Ferroptosisu2014A Novel Mechanism With Multifaceted Actions on Stroke, in the Journal: (JOURNAL)
  • how: The data showed that iron overload could lead to mitochondrial breakage of hippocampal neurons which significantly aggravated the early brain injury caused by intracerebral hemorrhage and that the outcome could be reversed by treatment with iron-chelating agents . The above data showed that under the pathological conditions of stroke GSH depletion and GPX4 . . .

     

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