Myt1l in the making: emerging insights on functions of a neurodevelopmental disorder gene

HIGHLIGHTS

  • who: Jiayang Chen from the (UNIVERSITY) have published the research work: MYT1L in the making: emerging insights on functions of a neurodevelopmental disorder gene, in the Journal: (JOURNAL) of 14/06/2022
  • how: Quantitative RT-PCR results showed that Myt1 and Myt1l were upregulated from E10.5 to E15.5 and then downregulated postnatally (Fig 2A) .
  • future: While the observed phenotypes during embryonic development are likely cell autonomous due to lack of mature glia at this developmental stage further studies (e_g single-cell_sequencing) are needed to deconvolve non-cell autonomous effects. The authors . . .

     

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