Flat dose regimen of toripalimab based on model-informed drug development approach

HIGHLIGHTS

  • who: January and colleagues from the Shanghai Tong University, China have published the paper: Flat dose regimen of toripalimab based on model-informed drug development approach, in the Journal: (JOURNAL)
  • what: The aim of this study is to provide pharmacological evidence for a flat dosing regimen of toripalimab by assessing the efficacy and safety profile of a 240 mg Q3W flat dose relative to the currently approved 3 mg/kg Q2W. The aim of this study was to provide pharmacokinetic evidence supporting flat dosage of toripalimab in antitumor therapy. Such a structure was deemed suitable . . .

     

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