HIGHLIGHTS
SUMMARY
In the study, combined with proven immunotherapy predictive markers, COAD of the high autophagy score group or high IFNG group tended to be "hot tumor" tissues and were more suitable for immune checkpoint inhibitor therapy. In the study, according to the respective median of autophagy score, IFNG, PD-L1 and CD8A expression, COAD patients were divided into the corresponding low and high groups. In (A) TCGA and_(B) GSE39582, the score of most immune signatures in the high IFNG group and high autophagy score group were significantly higher. higher expression of PD-L1, CD8A . . .
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