5-methoxytryptophan sensitizing head and neck squamous carcinoma cell to cisplatitn through inhibiting signal transducer and activator of transcription 3 (stat3)

HIGHLIGHTS

  • who: Yu-Chieh Su from the Dalin Tzu Hospital, Taiwan Kaohsiung Medical University, Taiwan have published the research work: 5-Methoxytryptophan Sensitizing Head and Neck Squamous Carcinoma Cell to Cisplatitn Through Inhibiting Signal Transducer and Activator of Transcription 3 (STAT3), in the Journal: (JOURNAL)
  • what: The authors aim to investigate the inhibitory effect and related mechanism of the combination treatment of CDDP and 5-MTP in HNSCC cells and 4nitroquinoline-1-oxide (4NQO)-induced oral tumor mouse model.
  • how: Collectively these results showed that CDDP inhibited cancer cell growth in a dose-dependent . . .

     

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