Daily fluctuations in kidney function in critically ill adults

HIGHLIGHTS

• who: Chao-Yuan Huang from the It is well known that the kidney function can change rapidly during critical illness, with either sudden increases [1] or decreases [2] in renal clearance that may have potentially important consequences for drug dosage adjustments involving renally excreted drugsHowever, the true incidence and degree of these fluctuations have never been described systematically. In this study, we aim to investigate kidney function fluctuations as defined by the daily differences in creatinine clearance (CrCl) in critically ill adults. For the present study, data were retrieved from patients included in the large multicenter EPaNIC . . .
  

   

  

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