Twist1 activates cancer stem cell marker genes to promote epithelial-mesenchymal transition and tumorigenesis in esophageal squamous cell carcinoma

HIGHLIGHTS

  • who: Sima Ardalan Khales from the Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran have published the research: TWIST1 activates cancer stem cell marker genes to promote epithelial-mesenchymal transition and tumorigenesis in esophageal squamous cell carcinoma, in the Journal: (JOURNAL)
  • what: The authors provide evidence that TWIST1 expression correlates with the expression of CSC markers in ESCC cell lines. The aim of this study was to identify how TWIST1 confers a CSC-like phenotype and induces changes in stem_cell marker expression in ESCC. The authors show that TWIST1 expression potentiates EMT . . .

     

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