Specific binding and endocytosis of liposomes to hek293t cells via myrisoylated pre-s1 peptide bound to sodium taurocholate cotransporting polypeptide

HIGHLIGHTS

  • who: Shuji Hinuma and collaborators from the Department of Biomolecular Science and Reaction, SANKEN, Osaka University, Mihogaoka, Osaka, Japan have published the research work: Specific Binding and Endocytosis of Liposomes to HEK293T Cells via Myrisoylated Pre-S1 Peptide Bound to Sodium Taurocholate Cotransporting Polypeptide, in the Journal: Vaccines 2022, 2050 of /2022/
  • what: The authors show here that the model system using liposomes to mimic HBV and NTCP interaction is simple and useful to chase the binding of nanoparticles to NTCP on the cell surface via Myr47 and following their endocytosis. The authors used HEK293T_cells . . .

     

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