A mitochondrial perspective on noncommunicable diseases

HIGHLIGHTS

  • who: Yifan Zheng et al. from the Sciences and Peking Union Medical College, Beijing, China have published the research: A Mitochondrial Perspective on Noncommunicable Diseases, in the Journal: Biomedicines 2023, 11, 647. of /2023/

SUMMARY

    In eukaryotes, mitochondria, organelles necessary for the maintenance of normal cellular physiological functions and production of adenosine_triphosphate (ATP) via tricarboxylic_acid_cycle and fatty_acid oxidation for cellular energy supply, function as the primary site of energy metabolism. Mitochondrial dysfunction, such as the rupture of the mitochondrial complex, mitochondrial uncoupling, and cristae remodeling and swelling, leads to an increase in Reactive . . .

     

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