HIGHLIGHTS
- who: Jordi Pfeifer Serrahima from the , Frankfurt, Germany Frankfurt Institute, Goethe University, Frankfurt have published the research work: Multivalent adaptor proteins specifically target NK cells carrying a universal chimeric antigen receptor to ErbB2 (HER2)-expressing cancers, in the Journal: (JOURNAL)
- how: As a prerequisite for further development of optimized UniCAR and TM combinations the authors investigated functionality of the recombinant target modules in comparative binding studies and cell killing experiments with ErbB2positive cancer cells of different solid tumor origins and NK cells carrying a first- or second-generation UniCAR. Data were evaluated using FlowJo software . . .
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