Integrating chromatin accessibility states in the design of targeted sequencing panels for liquid biopsy

HIGHLIGHTS

  • who: Pegah Taklifi from the DepartmentUniversity of have published the Article: Integrating chromatin accessibility states in the design of targeted sequencing panels for liquid biopsy, in the Journal: Scientific Reports Scientific Reports
  • what: The authors propose two types of target selection strategies (accessible and inaccessible) for each cancer type.
  • future: Although further research is needed to address early-stage cancer detection challenges the results provide a useful strategy for future targeted sequencing panel designs.

SUMMARY

    Since cfDNA in healthy individuals is known to mainly consist of blood-cell originating . . .

     

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