HIGHLIGHTS
- who: Christopher Daniel Morrone from the , Canada have published the research: Parvalbumin neuroplasticity compensates for somatostatin impairment, maintaining cognitive function in Alzheimeru2019s disease, in the Journal: (JOURNAL)
- what: In light of these findings, the authors propose that the TgF344-AD rats are an important rodent model to investigate contributions of neuronal compensatory mechanisms to cognition across AD progression.
- how: The authors utilized the TgF344-AD rat model as it recapitulates Au03b2 pathology hyperphosphorylation and deposition of tau into neuritic and pre-tangle inclusions and neurodegeneration including neuronal loss . The authors presented a novel . . .
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