Nmda receptor inhibition prevents intracellular sodium elevations in human olfactory neuroepithelial precursors derived from bipolar patients

HIGHLIGHTS

• who: Yonglin Gao from the DepartmentUniversity of have published the research work: NMDA receptor inhibition prevents intracellular sodium elevations in human olfactory neuroepithelial precursors derived from bipolar patients, in the Journal: Scientific Reports Scientific Reports
• what: Sodium regulation is central to neuronal function and may be disturbed in patients with bipolar disorder.

SUMMARY

The authors used cells that were at passage number 15-20. The NMDA receptor antagonist AP5 (D-2-amino5-phosphonopentanoate) was used to examine the role of NMDA receptor in normalizing this non-glutamate ionic stress, and was . . .

 



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