Atypical nmda receptor expression in a diffuse astrocytoma, myb- or mybl1-altered as a trigger for autoimmune encephalitis

HIGHLIGHTS

  • who: Marc Nikolaus from the (UNIVERSITY) have published the article: Atypical NMDA receptor expression in a diffuse astrocytoma, MYB- or MYBL1-altered as a trigger for autoimmune encephalitis, in the Journal: (JOURNAL) of 31/03/2022

SUMMARY

    In contrast to the MYB/MYBL1-altered astrocytoma, these tumors are usually not located in the cerebellum and do not contain dysmorphic neurons. Immunohistochemistry revealed atypical NR1-specific NMDAR positivity in somata of dysmorphic neurons detectable in the tumor (Fig 1p, q). This confirmed atypical NMDAR expression on the patient`s dysmorphic neurons and suggested that . . .

     

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