Differential activation of trpm8 by the stereoisomers of menthol

HIGHLIGHTS

• who: TRPM et al. from the Department of Biophysics, Kidney Disease Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Healthcare, Hangzhou, China have published the paper: Differential Activation of TRPM8 by the Stereoisomers of Menthol, in the Journal: (JOURNAL)
• what: The authors reason that such an increase in Kd for (+)-menthol is due to the relatively large Po_max (therefore the smaller decrease in L value) induced by_(+)-menthol at -80 mV . The authors reason that most likely in_(+)-neoisomenthol, its overall binding configuration was slightly changed so that how its isopropyl group . . .
  

   

  

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