Exposure of the basophilic cell line ku812 to liposomes reveals activation profiles associated with potential anaphylactic responses linked to physico-chemical characteristics

HIGHLIGHTS

  • who: Alexander J. Plant-Hately et al. from the Molecular and Integrative Biology, The University of Liverpool, Liverpool , NY, UK have published the research work: Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics, in the Journal: Pharmaceutics 2022, 14, 2470. of /2022/
  • what: The authors report the use of the human KU812 cell line as a surrogate for primary basophils. The aim of this study was to evaluate KU812 cell responses to known anaphylatoxins and liposomal materials of varying compositions, including . . .

     

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