Regulation of cocaine seeking behavior by locus coeruleus noradrenergic activity in the ventral tegmental area is time- and contingency-dependent

HIGHLIGHTS

  • who: Wojciech B. Solecki from the University of Colorado Denver, United States have published the paper: Regulation of cocaine seeking behavior by locus coeruleus noradrenergic activity in the ventral tegmental area is time- and contingency-dependent, in the Journal: (JOURNAL)
  • what: The authors report a time-dependent modulation of VTA circuitry - and, consequently, behavior - by NAergic LC afferents.
  • future: Work will also be needed to identify the inputs and mechanisms involved on both time-scales. (B) There were no differences in the number of cocaine infusions or (C) (D) lever responses during cocaine . . .

     

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