The impact of cannabinoids on inflammasome signaling in hiv-1 infection

HIGHLIGHTS

  • who: NeuroImmune Pharmacol. Ther. and colleagues from the (UNIVERSITY) have published the research: The impact of cannabinoids on inflammasome signaling in HIV-1 infection, in the Journal: (JOURNAL)
  • how: A similar observation was made between CB2R and CCR5 which acts as co-receptor for monotropic HIV-1 indicating that G protein-coupled CB2R can crosstalk with other G protein-coupled receptors mainly chemokine receptors and consequently affect heterologous signal_transduction pathways .

SUMMARY

    During acute HIV-1 infection, activated CD4+ T-cells are a significant target of HIV-1. The peripheral lymphoid tissues . . .

     

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