Single-exonuclease nanocircuits reveal the rna degradation dynamics of pnpase and demonstrate potential for rna sequencing

HIGHLIGHTS

• who: Zhiheng Yang from the (UNIVERSITY) have published the Article: Single-exonuclease nanocircuits reveal the RNA degradation dynamics of PNPase and demonstrate potential for RNA sequencing, in the Journal: (JOURNAL) of 17/08/2022
• what: Considering that the influence of the specific nucleoside is merely reflected in the coordination with amino_acids R93 and R97 through H-bonds, the authors focused on statistical analyses of the intermediate state (i.e., the RNA analog-bound structure). Limited by the natural property of the PNPase, which is suitable for the degradation of shortpiece RNAs, this approach has not . . .
  

   

  

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