Neutrophils in pancreatic cancer: potential therapeutic targets

HIGHLIGHTS

  • who: Wenkai Jiang from the Italy University Hospital in Halle, Germany have published the paper: Neutrophils in pancreatic cancer: Potential therapeutic targets, in the Journal: (JOURNAL)
  • what: GM-CSF-mediated increased neutrophil infiltration is the main reason that STAT5 promotes pancreatic fibrosis and chronic pancreatitis .
  • how: The results showed that DS-8273A eliminated polymorphonuclear MDSCs (PMN-MDSCs immature neutrophils) and prolonged progression-free survival .
  • future: Areas of future development Finding novel therapies is currently a hot spot and future research direction for cancer research. Including patients with chronic pancreatitis as a . . .

     

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