Motor deficits seen in microglial ablation mice could be due to non-specific damage from high dose diphtheria toxin treatment

HIGHLIGHTS

• who: Jiyun Peng from the Institute Nanchang University have published the paper: Motor deficits seen in microglial ablation mice could be due to non-specific damage from high dose diphtheria toxin treatment, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• how: Together the results indicated that high dose DT treatment non-specifically caused ataxia-like behavior and microglia activation even in WT mice.

SUMMARY

| https://doi.org/10.1038/s41467-022-31562-3 Similar to Rubino et_al`s report, the authors observed ataxia-like behaviors in the DTR mice with high dose . . .

 



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