Allergen-specific iga antibodies block ige-mediated activation of mast cells and basophils

HIGHLIGHTS

  • who: Yasmeen S. El Ansari from the Laboratory Medicine, Philipps University Marburg, Marburg, Germany, Department of Pediatrics, Harvard Medical School have published the Article: Allergen-Specific IgA Antibodies Block IgE-Mediated Activation of Mast Cells and Basophils, in the Journal: (JOURNAL)
  • future: While the results provide some evidence for a receptor-mediated inhibitory effect of antigen-specific IgA on mast cells further studies will be required to identify the relevant receptor mediating this effect. pathways the authors found that IgA suppresses IgE-induced cytokine production by mast cells in_vivo.

SUMMARY

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