Inhibition of notch signaling stimulates osteoclastogenesis from the common trilineage progenitor under inflammatory conditions

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  • who: Ma&scaron from the Department of Physiology and Immunology, University of School of Medicine, Laboratory for (NIH), United States have published the research work: Inhibition of Notch Signaling Stimulates Osteoclastogenesis From the Common Trilineage Progenitor Under Inflammatory Conditions, in the Journal: (JOURNAL)
  • what: The focus of the study was to characterize a bone marrow myeloid trilineage progenitor (also named MODP) of the adult mouse, with the ability to differentiate into three distinct myeloid lineages, namely osteoclasts, macrophages and dendritic cells, in the context of Notch signal modulation. The study design allowed the authors to . . .

     

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