Single-cell rna sequencing analysis reveals new immune disorder complexities in hypersplenism

HIGHLIGHTS

  • who: Hai-chao Zhao from the Complutense University of Madrid, Spain have published the research: Single-cell RNA Sequencing Analysis Reveals New Immune Disorder Complexities in Hypersplenism, in the Journal: (JOURNAL)
  • what: In this study, five spleen samples were collected and scRNA-seq was performed through the 10u00d7 Genomics sequencing platform.
  • how: In general the research found that abnormal distribution and proportion of T-cells can be a characteristic of HS these T-cell enriched functions and genes have certain characteristics which are mainly manifested through immunosuppression. showed that the specific B-cell . . .

     

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