HIGHLIGHTS
- who: Yanan Wu from the (UNIVERSITY) have published the article: Structures and mechanism of chitin synthase and its inhibition by antifungal drug Nikkomycin Z, in the Journal: (JOURNAL)
- what: The work provides new insights into the GT2 family of membrane-integrated GTs and highlights the Chs oligomer in chitin fibrillogenesis (see Supplementary Discussions).
SUMMARY
Inset, NikZ (as yellow stick) superimposed with its corresponding density (as blue mesh). h Coordination of NikZ in Chs1 active_site. In vitro activities of Chs1 active_site mutants with or without NikZ. j The reactants (reaction time: 16 . . .
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