Targeting srebp-1-mediated lipogenesis as potential strategies for cancer

HIGHLIGHTS

  • who: Qiushi Zhao from the National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life, Jilin University, Changchun, China, Department of Thoracic Surgery, The First have published the article: Targeting SREBP-1-Mediated Lipogenesis as Potential Strategies for Cancer, in the Journal: (JOURNAL)
  • what: The nuclear form of SREBP-1 (nSREBP-1) can bind to the promoter of protein kinase RNA-like endoplasmic_reticulum kinase (PERK) to augment its expression and phosphorylation, which might be the main reason that nSREBP-1 regulates cell proliferation, cell cycle . . .

     

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