HIGHLIGHTS
- who: Laura Gerosa from the of Neuroscience, CNR, Vedano al Lambro, Italy University of have published the Article: The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes, in the Journal: (JOURNAL) of May/24,/2022
- what: The authors demonstrate that associates with chromatin and with the chromatin remodeler lysine-specific demethylase 1 (LSD1) and regulates expression of genes (IEGs). Through the interplay with LSD1, the authors show that PCDH19 is able to regulate IEG expression in a way that suggests a homeostatic control of neuronal . . .
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