Removal of the e rnase activity and of the 3 9 untranslated region polyuridine insertion in a low-virulence classical swine fever virus triggers a cytokine storm and lethal disease

HIGHLIGHTS

  • who: VACCINES and collaborators from the Recerca en Sanitat Animal, Barcelona, Spain Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland have published the article: Removal of the E RNase Activity and of the 3 9 Untranslated Region Polyuridine Insertion in a Low-Virulence Classical Swine Fever Virus Triggers a Cytokine Storm and Lethal Disease, in the Journal: (JOURNAL) of 28/06/2022
  • what: The authors investigated the potential synergistic effect of the Erns RNase activity and the poly-U insertion in the 39 UTR on the regulation of innate and adaptive immunity . . .

     

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