Carbonic anhydrase ix-targeted -radionuclide therapy with 225ac inhibits tumor growth in a renal cell carcinoma model

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  • who: Robin I. J. Merkx and colleagues from the Department of Medical Imaging, Nuclear Medicine, Radboudumc, Nijmegen, The Netherlands have published the Article: Carbonic Anhydrase IX-Targeted -Radionuclide Therapy with 225Ac Inhibits Tumor Growth in a Renal Cell Carcinoma Model, in the Journal: Pharmaceuticals 2022, 570 of /2022/
  • what: The authors compared the tumor-targeting properties therapeutic efficacy and tolerability of the humanized antibody (hG250) labeled with either the u03b1-emitter actinium-225 (225 Ac) or the u03b2- -emitter lutetium-177 (177 Lu) in mice. The aim of the study was to evaluate the tumortargeting . . .

     

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