Phagocytosis converts infiltrated monocytes to microglia-like phenotype in experimental brain ischemia

HIGHLIGHTS

• who: Hyunwoo Ju from the Burke Neurological Institute, Mamaroneck Ave, White Plains, NY, USA have published the research: Phagocytosis converts infiltrated monocytes to microglia-like phenotype in experimental brain ischemia, in the Journal: (JOURNAL)
• what: This study shows that MDMs are the predominant in the brain with the u00adCD45High subset having the highest phagocytic activity levels. The authors show that infiltrating MDMs in the post-ischemic brain convert to a microglia-like phenotype following phagocytic activity. Together, this study shows that MDMs are the major phagocytic cell type in the ischemic brain and have plastic . . .
  

   

  

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