Igg fusion proteins for brain delivery of biologics via blood-brain barrier receptor-mediated transport

HIGHLIGHTS

• who: Ruben J. Boado from the Department of Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA, USA have published the Article: IgG Fusion Proteins for Brain Delivery of Biologics via Blood-Brain Barrier Receptor-Mediated Transport, in the Journal: Pharmaceutics 2022, 1476 of /2022/
• what: The aim of this article is to review this generation of IgG fusion_proteins. The GLP toxicological study aimed for an acute treatment of stroke was completed with IV doses of up to 50 mg/kg BW of fusion_protein over a 60 h period to 56 primates .
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