Molecular signatures of in situ to invasive progression for basal-like breast cancers: an integrated mouse model and human dcis study

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  • who: Aatish Thennavan from the Animal model details All animal work was carried out in University of North Carolina Division of Laboratory and Animal Medicine (UNC DLAM) facilities in compliance with Institutional Animal Care and Use Committee (IACUC) approved protocolsFemale FVB/NJ and, (1)-Tag mice were obtained in collaboration with the UNC Lineberger Comprehensive Cancer Center (LCCC) Mouse Phase I Unit (MP U)., (1)-Tag mice transgenic model produces spontaneous mammary tumors and were originally developed in the FVB/NJ background15. Animals were cared for according to the recommendations of the Panel on Euthanasia of the . . .

     

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