Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer

HIGHLIGHTS

  • who: Qing-Fang Han from the (UNIVERSITY) have published the research: Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer, in the Journal: (JOURNAL)
  • what: The authors provide a comprehensive overview of strategies and inhibitors targeting exosome biogenesis and highlight the perspective of pharmacological targeting of exosome generation in cancer therapy.
  • future: Study is needed to determine whether these RNAs cooperate with RBPs to form condensates and actively contributes to their exosomal sorting. Study is needed to investigate how hnRNPK is captured by lipid raft on limiting membrane and whether the LC3conjugation system . . .

     

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