Dexmedetomidine alleviates inflammatory response and oxidative stress injury of vascular smooth muscle cell via α2ar/gsk-3β/mkp-1/nrf2 axis in intracranial aneurysm

HIGHLIGHTS

• who: Ze Zhang from the Before the study, written informed consents were obtained from the patients, and this study was granted approval of the Ethics Committee of The First Hospital of Hebei Medical University (Ethical approval:, , )All participates were over , years of age. The study protocols were also based on the ethical principles of the Declaration of Helsinki for medical research involving human subjects. , patients with IA participated in this study. IA tissue samples were obtained during the surgery, and superficial temporal artery (STA) vascular tissue samples were collected as controls. All samples were fixed in, % formaldehyde . . .
  

   

  

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